M. B. Strauss, M.D., F.A.C.P.
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Sufficient data are now available concerning ten patients to characterize the clinical and pathological findings in this disorder. In none was the urinary sediment abnormal, and albuminuria was either absent or minimal.
Six of the patients, aged eight to 18 years, presented with severe anemia of obscure etiology. The unexpected finding of azotemia led to further investigation which revealed hyposthenuria refractory to vasopressin, acidosis, hypocalcemia, hyperphosphatemia, hyperphosphatasia, roentgenologic evidence of bone disease, and an inability to conserve sodium chloride. Hypertension was absent. The anamnesis disclosed long-standing polyuria and nocturia that had never been considered unusual or abnormal. Survival, once diagnosis
Strauss MB. Clinical and Pathological Aspects of Cystic Disease of the Renal Medulla.. Ann Intern Med. 1962;56:699. doi: https://doi.org/10.7326/0003-4819-56-4-699
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Published: Ann Intern Med. 1962;56(4):699.
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