B. Lown, M.D.
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Since the introduction of quinidine by Frey, 45 years ago, drugs have been the mainstay in the treatment of ectopic arrhythmias. A new method of treatment has now been introduced which no longer depends on drugs. This method, cardioversion, is based on 2 key principles.
1. The heart can be depolarized across the intact chest by a brief direct-current (d-c) electrical discharge and thereby result in abolition of an ectopic arrhythmia.
2. When the d-c discharge is synchronized to fall outside the vulnerable period of the cardiac cycle, the discharge is entirely without hazard to the patient.
Cardioversion has now
Lown B. The Termination of Cardiac Arrhythmias with Electrical Discharge.. Ann Intern Med. 1963;58:713. doi: https://doi.org/10.7326/0003-4819-58-4-713_2
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Published: Ann Intern Med. 1963;58(4):713.
Cardiology, Rhythm Disorders and Devices.
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