PETER T. KUO, M.D., D.SC., F.A.C.P.; DAVID R. BASSETT, M.D.
The clinically encountered hyperlipidemic states differ from one another in the type of lipid abnormalities observed in the plasma and tissues and the manner in which these abnormalities are produced. The primary hyperlipidemias are states in which the plasma lipid abnormalities are frequently related to a genetic defect, in contrast to hyperlipidemias secondary to specific metabolic disorders. The importance of these primary hyperlipidemias in the development of atherosclerosis has been well recognized (1-4).
In differentiating the various types of hyperlipidemia, extensive investigations have been made of the serum lipoproteins and serum lipids of hyperlipidemic patients (5-10). Efforts have also been
KUO PT, BASSETT DR. Primary Hyperlipidemias and Their Management. Ann Intern Med. 1963;59:495–507. doi: 10.7326/0003-4819-59-4-495
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Published: Ann Intern Med. 1963;59(4):495-507.
Cardiology, Coronary Risk Factors, Dyslipidemia.
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