FREDERICK H. WELLAND, M.D.; DONALD P. TSCHUDY, M.D.
This report describes a patient in whom symptoms of an inflammatory spinal lesion mimicked an attack of previously diagnosed but latent acute intermittent porphyria (AIP). The osteomyelitic process and the stress of surgical procedures affected the quantity of δ-aminolevulinic acid and porphobilinogen excreted by the patient. In addition, the patient has gout, a second "inborn error of metabolism." This is of interest since low serum uric acid levels have been reported in patients with AIP (1) and decreased urate production has been observed in experimental porphyria (2).
L. W. C., (045159) a 56-year-old white male machinist, was admitted
WELLAND FH, TSCHUDY DP. The Effects of Spinal Osteomyelitis on Porphyrin-Precursor Excretion, and the Presence of Gout in a Patient with Latent Acute Intermittent Porphyria. Ann Intern Med. ;59:547–553. doi: 10.7326/0003-4819-59-4-547
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Published: Ann Intern Med. 1963;59(4):547-553.
Gastroenterology/Hepatology, Gout, Infectious Disease, Liver Disease, Rheumatology.
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