RAYMOND D. MUTTER, M.D.; MYRON TANNENBAUM, M.D., PH.D.; JOHN E. ULTMANN, M.D., F.A.C.P.
Urticaria pigmentosa was first described in 1869 by Nettleship (1) and named by Sangster (2) in 1878. In this disease, mast cell infiltration is confined entirely to the skin. By 1923, 306 cases had been reported in the dermatologic literature (3), and at present over 600 cases have been recorded. In 1933, Touraine, Solente, and Renault (4) described urticaria pigmentosa with mast cells involving organs other than the skin. Since then, a total of 28 cases with systemic mast cell disease have been reported (4-30).
The mast cell or tissue basophil was described, as well as named, by Paul Ehrlich
MUTTER RD, TANNENBAUM M, ULTMANN JE. Systemic Mast Cell Disease. Ann Intern Med. 1963;59:887–906. doi: 10.7326/0003-4819-59-6-887
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Published: Ann Intern Med. 1963;59(6):887-906.
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