HIROSHI YAMAUCHI, M.D.; JAMES HOPPER JR., M.D.
Clinical descriptions of circulatory insufficiency in the nephrotic syndrome are few despite the established observation that a reduction in blood volume is found in this disease state (1-15). According to Squire (13), total blood volume in patients with the nephrotic syndrome may be decreased to 70 to 80 per cent of normal. Acute decreases in blood volume of this magnitude in other clinical situations have often been associated with shock or hypotension (16-21).
Between 1944 and 1960, we have seen the occurrence of shock or hypotension in 10 adult patients with the nephrotic syndrome. The patients were studied during periods
YAMAUCHI H, HOPPER J. Hypovolemic Shock and Hypotension as a Complication in the Nephrotic Syndrome: Report of Ten Cases. Ann Intern Med. ;60:242–254. doi: 10.7326/0003-4819-60-2-242
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Published: Ann Intern Med. 1964;60(2_Part_1):242-254.
Nephrology, Nephrotic Syndrome.
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