William C. Heath, M.B., B.S.; Edward D. Freis, M.D., F.A.C.P.
This content is PDF only. Please click on the PDF icon to access.
The pteridine diuretic triamterene, 100 mg twice daily, did not alter the urinary potassium excretion control values when given to seven nonedematous inpatients. In view of the saluretic potency of the benzothiadiazines and the potassium sparing action of triamterene, a combination of the two drugs was evaluated in 13 patients on a controlled sodium intake. Sodium excretion averaged 154 mEq/24 hr during control; 332 with hydrochlorothiazide, 50 mg, twice daily; and 341 mEq/24 hr with hydrochlorothiazide, 25 mg plus triamterene 50 mg, twice daily. Potassium increased from 60 to 80 mEq/24 hr with hydrochlorothiazide but decreased to 50 mEq with
Heath WC, Freis ED. Triamterene and Hydrochlorothiazide in the Treatment of Hypertension.. Ann Intern Med. 1964;60:317. doi: https://doi.org/10.7326/0003-4819-60-2-317_2
Download citation file:
Published: Ann Intern Med. 1964;60(2_Part_1):317.
Cardiology, Coronary Risk Factors, Hypertension, Nephrology.
Results provided by:
Copyright © 2019 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use