Sigmundur Gudbjarnason, M.D.; Richard J. Bing, M.D., F.A.C.P.; Chiyo Chiba, M.D.; Christian DeSchryver, M.D.; Jiro Yamanaka, M.D.
This content is PDF only. Please click on the PDF icon to access.
Myocardial infarction was produced in dogs by ligation of branches of the coronary arteries. The rate of incorporation of a radioactive amino acid, glycine-2-C14, into heart muscle protein was studied over a period of six weeks. Three samples were analyzed from each left ventricle close to the infarcted area: normal tissue, the infarcted area, and borderline tissue.
The infarcted tissue showed a rapid diminution in protein synthesis after infarction, but already on the third day, the incorporation into the infarcted tissue rose above the normal and reached a maximum after 4 days. This reflects the early destruction and the following
Gudbjarnason S, Bing RJ, Chiba C, DeSchryver C, Yamanaka J. The Reaction of the Heart to Myocardial Infarction.. Ann Intern Med. 1964;60:320–321. doi: 10.7326/0003-4819-60-2-320_3
Download citation file:
Published: Ann Intern Med. 1964;60(2_Part_1):320-321.
Acute Coronary Syndromes, Cardiology, Coronary Heart Disease, Emergency Medicine.
Results provided by:
Copyright © 2019 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use