B. J. Kennedy, M.D., F.A.C.P.
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Androgenic hormone increases erythropoiesis when administered in massive doses for a prolonged period. Furthermore, in depression of bone marrow function by toxic agents or disease, improvement of leukopenia and thrombocytopenia have been inconsistently observed.
Androgenic hormones have been administered to patients with advanced malignancies in an attempt to allow chemotherapeutic agents to be employed more effectively. The hormone was administered to patients with (1) depressed marrow due to tumor; (2) depressed marrow due to previous cytotoxic therapy or irradiation therapy; and (3) normal marrow prior to intensive cytotoxic therapy. When the androgenic hormone was administered for more than 6 weeks,
Kennedy BJ. Stimulation of Hematopoiesis by Androgenic Hormone.. Ann Intern Med. 1964;60:327. doi: https://doi.org/10.7326/0003-4819-60-2-327_2
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Published: Ann Intern Med. 1964;60(2_Part_1):327.
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