HARRISON F. WOOD, M.D.; ALVAN R. FEINSTEIN, M.D.; ANGELO TARANTA, M.D.; JEANNE A. EPSTEIN, M.D.; RITA SIMPSON, B.A.
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The preceding report presented the aims, background, and methods of a large-scale study of three types of prophylaxis against streptococcal infections and recurrences of rheumatic fever (1). It described the characteristics of the 431 rheumatic children and adolescents who were studied in a large metropolitan area, the organization of the clinic, the procedures used to assign patients to the three prophylactic regimens in a statistically comparable manner, and certain preliminary results.
The present report will assess the effectiveness of the three prophylactic regimens during the study, the numbers and rates of streptococcal infections and rheumatic fever recurrences, and the nature
WOOD HF, FEINSTEIN AR, TARANTA A, et al. Rheumatic Fever in Children and Adolescents: A Long-term Epidemiologic Study of Subsequent Prophylaxis, Streptococcal Infections, and Clinical Sequelae: III. Comparative Effectiveness of Three Prophylaxis Regimens in Preventing Streptococcal Infections and Rheumatic Recurrences. Ann Intern Med. 1964;60:31–46. doi: 10.7326/0003-4819-60-2-31
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Published: Ann Intern Med. 1964;60(2_Part_2):31-46.
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