LOUIS TOBIAN, M.D., F.A.C.P.; SANDRA SCHONNING, B.S.; CAROL SEEFELDT, B.S.
Many observations suggest that the mammalian kidney has an important effect on arterial pressure. Either narrowing the renal artery (1) or compressing the kidney parenchyma (2) will induce arterial hypertension. Various renal diseases such as chronic glomerulonephritis or polycystic kidneys may bring on severe arterial hypertension. The surgical correction of a narrowed renal artery in man often produces a complete cure of an existing hypertension. Moreover, if one identical twin has severe hypertension resulting from chronic glomerulonephritis, the transplantation of a normal kidney from the other twin may bring about the disappearance of his hypertension (3).
Knowing that the kidney
TOBIAN L, SCHONNING S, SEEFELDT C. The Influence of Arterial Pressure on the Antihypertensive Action of a Normal Kidney, a Biological Servomechanism. Ann Intern Med. 1964;60:378–383. doi: 10.7326/0003-4819-60-3-378
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Published: Ann Intern Med. 1964;60(3):378-383.
DOI: 10.7326/0003-4819-60-3-378
Cardiology, Coronary Risk Factors, Hypertension, Nephrology.
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