A. McChesney Evans, M.D., F.A.C.P.
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Bilateral thrombophlebitis of the legs with pulmonary embolism heralded the onset of a case of hemorrhagic thrombocythemia 17 years ago in a 28-year-old white female. Multiple life-threatening thrombotic and hemorrhagic manifestations during periods of elevated platelet counts as high as 6 million/mm3 are described. Spontaneous abortion, splenic vein thrombosis, epistaxis, hypermenorrhea and repeated severe upper gastrointestinal bleeding requiring 71 units of blood complicated the course. Typical megakaryocytosis of the bone marrow is illustrated. Treatment with 14.3 µc of radio phosphorus32 over a 3-year period was followed by 6 symptom-free years. She maintains mean normal blood and bone marrow values to
Evans AM. Hemorrhagic Thrombocythemia.. Ann Intern Med. 1964;60:727–728. doi: https://doi.org/10.7326/0003-4819-60-4-727_3
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Published: Ann Intern Med. 1964;60(4):727-728.
Coagulopathies, Hematology/Oncology, Platelet Disorders.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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