J. H. Felts, M.D., F.A.C.P.; H. H. Bradshaw, M.D.; D. D. Anderson, M.D.; J. E. Whitley, M.D.
This content is PDF only. Please click on the PDF icon to access.
Azotemic osteodystrophy results from secondary hyperparathyroidism and is manifested by typical bony changes, an elevated alkaline phosphatase and, often, a high normal serum calcium concentration. With progression, bone pain and spontaneous fractures lead to skeletal deformity and invalidism. Treatment with oral alkali is ineffective but vitamin D in oral doses to 200,000 units daily usually relieves symptoms within 6 weeks and induces recalcification of bone. Hypervitaminosis D becomes a constant threat to renal function during therapy but skeletal symptoms recur quickly when calciferol is discontinued.
In November, 1960, a 38-year-old woman with azotemia, elevated serum alkaline phosphatase and radiographically classical
Felts JH, Bradshaw HH, Anderson DD, Whitley JE. Management of Azotemic Osteodystrophy.. Ann Intern Med. 1964;60:737. doi: 10.7326/0003-4819-60-4-737_1
Download citation file:
Published: Ann Intern Med. 1964;60(4):737.
Results provided by:
Copyright © 2019 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use