ROBERT L. SCHEER, M.D.; MURRAY A. GROSSMAN, M.D.
The simultaneous appearance of pulmonary hemorrhage and an acute glomerulonephritis has been observed often enough to warrant the conclusion that this represents a distinct clinical entity (1-12). This disease has been called Goodpasture's syndrome, although there is some doubt that the patient described by Goodpasture in 1919 actually met the criteria for the syndrome (1). Numerous reports have emphasized the fulminant course of the disease. The etiology of this syndrome is obscure, but the nature of the tissue reaction suggests that an immune mechanism is at least partially responsible for its pathogenesis. Immunologic studies of two women who died of
SCHEER RL, GROSSMAN MA. Immune Aspects of the Glomerulonephritis Associated with Pulmonary Hemmorhage. Ann Intern Med. 1964;60:1009–1021. doi: 10.7326/0003-4819-60-6-1009
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Published: Ann Intern Med. 1964;60(6):1009-1021.
Nephrology, Pulmonary/Critical Care.
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