ALVAN R. FEINSTEIN, M.D.
Physicians generally believe that human cancer is most curable when found early and excised completely. In this concept, a tumor is found "early" if confined to its primary site without regional or distant dissemination, and is "excised completely" if surgically removed together with an appropriate margin of normal tissue. Results of treatment for cancer confirm the concept consistently, and show survival rates that are best in patients with resectable tumors, and worst in those with lesions discovered too "late" to be removed.
This rule of surgical therapy is regularly violated by exceptions. Some patients who come to treatment promptly after
FEINSTEIN AR. Symptomatic Patterns, Biologic Behavior, and Prognosis in Cancer of the Lung: Practical Application of Boolean Algebra and Clinical Taxonomy. Ann Intern Med. 1964;61:27–43. doi: 10.7326/0003-4819-61-1-27
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Published: Ann Intern Med. 1964;61(1):27-43.
Hematology/Oncology, Lung Cancer, Pulmonary/Critical Care.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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