ALEXANDER M. RUTENBURG, M.D.; BENJAMIN M. BANKS, M.D.; ESTEBAN P. PINEDA, M.D.; JULIUS A. GOLDBARG, M.D.
Diseases of the liver, bile duct, or pancreas generally produce an increase in serum aminopeptidase activity (LAP) (1-14). This increase signifies excretory blockade (1, 6). The same is true of serum phosphatase, but an increase in this enzyme can also be caused by increased osteoblastic activity (15-26).
Previous reports (1, 3, 4, 6-8, 12, 27-34) have dealt with these serum enzymes in jaundiced patients, but the data on anicteric patients (3-6, 27, 28) are sparse. The purpose of the present report is to assess the relative merits of the serum values of these enzymes in 1,332 anicteric patients, 400 in
RUTENBURG AM, BANKS BM, PINEDA EP, GOLDBARG JA. A Comparison of Serum Aminopeptidase and Alkaline Phosphatase in the Detection of Hepatobiliary Disease in Anicteric Patients. Ann Intern Med. ;61:50–55. doi: 10.7326/0003-4819-61-1-50
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Published: Ann Intern Med. 1964;61(1):50-55.
Biliary Disorders, Celiac Disease and Malabsorption, Education and Training, Gastroenterology/Hepatology, Hospital Medicine.
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