J. E. ULTMANN, M.D., F.A.C.P.; R. D. MUTTER, M.D.; M. TANNENBAUM, M.D.; R. R. P. WARNER, M.D., F.A.C.P.
In 1869, Nettleship (1) described macular lesions of the skin that became edematous on rubbing; these were called urticaria pigmentosa by Sangster (2). Touraine, Solente, and Renault (3), in 1933, first reported a case of urticaria pigmentosa with mast cells involving organs other than the skin. Although over 600 cases of urticaria pigmentosa have been described, only 29 patients with systemic mast cell disease are on record (4). A patient diagnosed at the Francis Delafield Hospital as having systemic mast cell disease afforded us the opportunity to study this rare and interesting entity and to correlate the clinical manifestations with
ULTMANN JE, MUTTER RD, TANNENBAUM M, WARNER RRP. Clinical, Cytologic, and Biochemical Studies in Systemic Mast Cell Disease. Ann Intern Med. ;61:326–333. doi: 10.7326/0003-4819-61-2-326
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Published: Ann Intern Med. 1964;61(2):326-333.
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