M. A. Sullivan, M.D.; D. K. Miller, M.D., F.A.C.P.; E. R. Gabrieli, M.D.
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To establish criteria for objectively assessing liver status of alcoholics, 35 selected cases in various clinical stages of cirrhosis were investigated in a specially designed metabolic unit. Data about each patient's history and clinical symptoms were coded for processing. Then after arbitrarily establishing criteria for four clinical grades of severity each case was placed into this scale by considering alcoholic history, nutritional data, rate and degree of recovery from acute phase after admission to hospital, initial liver size, and time course of its decrease. Liver biopsy was also graded into four groups by an experienced pathologist. Special metabolic measurements included
Sullivan MA, Miller DK, Gabrieli ER. A Quantitative Approach to Clinical, Histologic, and Biochemical Evaluation of Liver Cirrhosis.. Ann Intern Med. 1964;61:803. doi: https://doi.org/10.7326/0003-4819-61-4-803_2
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Published: Ann Intern Med. 1964;61(4):803.
Gastroenterology/Hepatology, Liver Disease.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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