Donald H. Hanscom, M.D.; James V. Dunphy, M.D.; Armand Littman, M.D., Ph.D., F.A.C.P.
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Our previous dose-response data on pancreozymin (PZ) in humans indicated progressively better discrimination between normal and pancreatic patients with increasing doses of PZ. With the new Jorpes-Mutt preparation of PZ it is possible to give still larger doses. A clinical test was developed measuring the protein (enzyme) output from the pancreas in response to intravenously injected PZ (Cecekin, Vitrum, Stockholm). A double lumen Dreiling tube collected gastric and duodenal contents separately. A secretin test was done by inecting 1.5 µ/kg of secretin and collecting six 10-min samples. Then secretin was given by continuous intravenous infusion at a rate of 1.5
Hanscom DH, Dunphy JV, Littman A. The Output of Pancreatic Protein after Pancreozymin: A Test of Pancreatic Exocrine Function.. Ann Intern Med. ;61:804–805. doi: 10.7326/0003-4819-61-4-804_4
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Published: Ann Intern Med. 1964;61(4):804-805.
Gastroenterology/Hepatology, Pancreatic Disease.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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