J. Alfred Rider, M.D., Ph.D., F.A.C.P.; Ernesto J. Puletti, M.D.; Hugo C. Moeller, M.D., Ph.D.
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Biochemical and gross pathologic changes were studied in more than 150 patients who were subjected to gastric hypothermia for the treatment of duodenal ulcer. Control gastroscopic examinations, gastric analyses for free HCl, pepsin, and 24-hr uropepsin levels were determined. Twenty-four hours after hypothermia, there was a two- to three-fold rise in uropepsin with a decrease in free HCl averaging approximately 60%. There was a direct correlation between intragastric temperature depression and depression of gastric acidity. Gastroscopic examination immediately after the hypothermia and a day later revealed mild to moderate submucosal hemorrhages. Repeat examinations from several days to several weeks later
Rider JA, Puletti EJ, Moeller HC. The Study of Mucosal and Biochemical Changes after Gastric Hypothermia.. Ann Intern Med. ;61:805. doi: 10.7326/0003-4819-61-4-805_1
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Published: Ann Intern Med. 1964;61(4):805.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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