John F. Murray, M.D.
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Coccidioidomycosis occurs in acute and chronic varieties; most of the former are subclinical, but respiratory diseases that range from mild flu-like illnesses to severe pneumonias may occur. Pleural effusion, hilar lymphadenopathy, or erythema nodosum may be the predominant manifestation and cause diagnostic confusion unless coccidioidomycosis is considered. Pulmonary infections in very young, aged, debilitated, pregnant, or dark-skinned individuals can be serious. Treatment should be considered both for the clinical problem itself and to prevent spread. The most frequent complication is dissemination that usually occurs early and has a predilection for skin, bones, lung, lymph nodes, and meninges. Diagnostic aids include
Murray JF. Clinical Manifestations of Coccidioidomycosis.. Ann Intern Med. 1964;61:807. doi: 10.7326/0003-4819-61-4-807_1
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Published: Ann Intern Med. 1964;61(4):807.
DOI: 10.7326/0003-4819-61-4-807_1
Infectious Disease.
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