William L. Hewitt, M.D., F.A.C.P.
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Coccidioidomycosis starts as an acute primary pulmonary infection that is asymptomatic in over 60% of all cases. Its symptomatic form may vary from an influenza-like illness to severe pneumonia. Healing may follow the primary infection, residuals may persist or dissemination may occur. The only successful chemotherapy for coccidioidomycosis is amphotericin B. Meningitis may be maintained in prolonged remission by long continued, periodic intracathecal treatment. The nephrotoxicity of amphotericin is the greatest limiting factor in chemotherapy.
Hewitt WL. Coccidioidomycosis.. Ann Intern Med. ;61:807. doi: 10.7326/0003-4819-61-4-807_3
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Published: Ann Intern Med. 1964;61(4):807.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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