Herbert J. Robb, M.D.; Prescott Jordan, M.D.; Lyle F. Jacobson, M.D.
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While making high magnification observations of the bowel, mesentery, and lung, we have observed that microemboli commonly develop in association with hemorrhagic shock, trauma, and endotoxin shock. These same platelet and cellular aggregates can be consistently produced and observed in anaphylactic shock. Once these aggregates develop they break loose causing a mechanical blockage of the circulation at distal points of narrowing.
Cinephotomicrography has been used to record the formation and embolization of the platelet aggregates during the production of anaphylactic shock. Clear pictures are available of the emboli as they lodge in the lung producing a slowing and blockage of
Robb HJ, Jordan P, Jacobson LF. The Role of Microembolism in Anaphylactic Shock.. Ann Intern Med. 1964;61:810. doi: https://doi.org/10.7326/0003-4819-61-4-810_2
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Published: Ann Intern Med. 1964;61(4):810.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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