MARTIN NYDICK, M.D.; ELLIS SAMOLS, M.B., M.R.C.P.; TAKESHI KUZUYA, M.D.; ROBERT H. WILLIAMS, M.D., F.A.C.P.
In patients with hypoglycemia, the etiologic diagnosis depends on an interpretation of the response of the blood sugar to various provocative tests, usually including the administration of glucose, tolbutamide, L-leucine, and a prolonged fast. Plasma insulin assay appears to improve diagnostic accuracy, although the importance of its contribution can only be assessed after extensive experience. The following report of a difficult differential diagnostic problem is of particular interest as it represents the first description of the behavior of serum insulin in a patient with diabetes mellitus and reactive hypoglycemia; and in addition, some of the data bear on the question
NYDICK M, SAMOLS E, KUZUYA T, et al. A Difficult Diagnostic Problem in Spontaneous Hypoglycemia: Reactive Hypoglycemia in Mild Diabetes Mellitus. Ann Intern Med. 1964;61:1122–1127. doi: https://doi.org/10.7326/0003-4819-61-6-1122
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Published: Ann Intern Med. 1964;61(6):1122-1127.
Cardiology, Coronary Risk Factors, Diabetes, Endocrine and Metabolism.
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