PAUL KEZDI, M.D.; MISHA S. ZAKS, PH.D.; H. JOAN COSTELLO, M.S.; BENJAMIN BOSHES, M.D., PH.D.
A number of authors have observed that cardiac dysfunctions, particularly mitral and aortic valve deformities, are frequently associated with neurologic symptoms (1-3). Clinical observations of minor neurologic dysfunctions involve, among other signs, complaints of dizziness, attacks of syncope, confusional episodes, and paresthesias. The exact causes of these symptoms, however, are not usually assessed with any degree of accuracy.
Several authors have found a relationship between mitral valve disease and central nervous system impairments, particularly cerebral embolism. In cases of cerebral embolism, Carter (4) observed 52% having mitral stenosis with atrial arrhythmia and 8% having stenosis with sinus rhythm. The frequency
KEZDI P, ZAKS MS, COSTELLO HJ, et al. The Impact of Chronic Circulatory Impairment on Functioning of Central Nervous System. Ann Intern Med. 1965;62:67–79. doi: https://doi.org/10.7326/0003-4819-62-1-67
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Published: Ann Intern Med. 1965;62(1):67-79.
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