Skip Navigation
Menu
Original Research |1 January 1965

The Detection of Intestinal Absorption of Co57 Tagged Vitamin B12 by Serum Counting

PAUL R. MCCURDY, M.D.

FULL TEXT

Abstract

The usual cause for vitamin B12 deficiency is its specific malabsorption caused by lack of gastrict intrinsic factor. Nonsurgical deficiency of intrinsic factor is pernicious anemia. The Schilling test was devised to measure gastrointestinal absorption of vitamin B12 (1). In it is measured the radioactivity flushed out in the urine during the 24 hours after the oral administration of B12 tagged with a radioactive isotope of cobalt. To differentiate true Addisonian pernicious anemia from other causes of failure to absorb vitamin B12 unrelated to the secretion of gastric intrinsic factor, one should repeat an abnormal Schilling test and give a

FULL TEXT
PDF
Not Available
Citations
Citation

MCCURDY PR. The Detection of Intestinal Absorption of Co57 Tagged Vitamin B12 by Serum Counting. Ann Intern Med. 1965;62:97–102. doi: 10.7326/0003-4819-62-1-97

Download citation file:

© 2019

×
Permissions

Published: Ann Intern Med. 1965;62(1):97-102.

DOI: 10.7326/0003-4819-62-1-97

25 Citations

Related Articles
MALABSORPTION SYNDROME: INTESTINAL ABSORPTION OF VITAMIN B1212
Annals of Internal Medicine; 48 (1): 30-38
Combined therapy with folic acid and vitamins B6 and B12 did not affect cancer risk in women at high risk for CV disease
Annals of Internal Medicine; 150 (6): JC3-9
Elevated Methylmalonic Acid and Total Homocysteine Levels Show High Prevalence of Vitamin B12 Deficiency after Gastric Surgery
Annals of Internal Medicine; 124 (5): 469-476
Impaired Antibody Responses to Pneumococcal Polysaccharide in Elderly Patients with Low Serum Vitamin B12 Levels
Annals of Internal Medicine; 124 (3): 299-304
View MoreView Less

Journal Club
Combined therapy with folic acid and vitamins B6 and B12 did not affect cancer risk in women at high risk for CV disease
Annals of Internal Medicine; 150 (6): JC3-9
View MoreView Less

Related Topics
Adrenal Disorders
Celiac Disease and Malabsorption
Endocrine and Metabolism
Gastroenterology/Hepatology
Hematology/Oncology

Adrenal Disorders, Celiac Disease and Malabsorption, Endocrine and Metabolism, Gastroenterology/Hepatology, Hematology/Oncology.

PubMed Articles
Vitamin D affects insulin sensitivity and β-cell function in obese non-diabetic youths.
Eur J Endocrinol 2019.
A novel nutritional supplement to reduce plasma homocysteine in nonpregnant women: A randomised controlled trial in The Gambia.
PLoS Med 2019;16(8):e1002870.
View More

Results provided by: PubMed

CONTINUE WITH LIMITED ACCESS
Annals of Internal Medicine
To receive access to the full text of freely available articles, alerts, and more. You will be directed to acponline.org to complete your registration.
×
acp link acp
silverchair link silverchair

Copyright © 2019 American College of Physicians. All Rights Reserved.

Print ISSN: 0003-4819 | Online ISSN: 1539-3704

Privacy Policy

|

Conditions of Use

This site uses cookies. By continuing to use our website, you are agreeing to our privacy policy. | Accept
×

You need a subscription to this content to use this feature.

×
PDF Downloads Require Access to the Full Article.
Annals of Internal Medicine
To receive access to the full text of freely available articles, alerts, and more. You will be directed to acponline.org to complete your registration.
×
Access to this Free Content Requires Users to be Registered and Logged In. Please Choose One of the Following Options
Annals of Internal Medicine
To receive access to the full text of freely available articles, alerts, and more. You will be directed to acponline.org to complete your registration.
×