MAXWELL M. WINTROBE, M.D.
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The immediate problems related to adverse reactions to drugs are the need to  assemble the information,  evaluate the data, and  disseminate the information so gathered. More fundamental are the need to  gain an understanding of the mechanisms involved in the development of adverse reactions to drugs,  obtain conclusive proof of cause and effect relationships suggested by circumstantial evidence, and  develop techniques for predicting ill effects. However, difficulties in securing fundamental information need not delay the institution of practical steps for the protection of mankind.
Some have assumed that if a drug were tested in
WINTROBE MM. Reporting of Adverse Reactions to Drugs. Ann Intern Med. 1965;62:170–174. doi: https://doi.org/10.7326/0003-4819-62-1-170
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Published: Ann Intern Med. 1965;62(1):170-174.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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