Charles C. J. Carpenter, M.D.; R. Bradley Sack, M.D.; Sam A. Wells, M.D.; Peter E. Dans, M.D.; Rabindra N. Chaudhuri
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An effective fluid repletion regimen for treatment of Asiatic cholera has previously been delineated. During the 1963 and 1964 epidemics in Calcutta, a series of carefully controlled studies were carried out in order to (1) clarify the role of antibiotics in the treatment of cholera; (2) compare the relative efficacy of lactate and bicarbonate in correcting the acidosis; and (3) determine a practical means of estimating intravenous fluid requirements of cholera patients in epidemic situations. The studies included 120 hypotensive adult males, all of whom were treated by a basic fluid repletion regimen of isotonic saline and isotonic sodium lactate
Carpenter CCJ, Sack RB, Wells SA, et al. Therapeutic Studies in Asiatic Cholera.. Ann Intern Med. 1965;62:1090–1091. doi: https://doi.org/10.7326/0003-4819-62-5-1090_4
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Published: Ann Intern Med. 1965;62(5):1090-1091.
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