G. Lennard Gold, M.D., F.A.C.P.; Bruce I. Shnider, M.D., F.A.C.P.; John J. Lynch, M.D.
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In the early 1940's mechlorethamine, nitrogen mustard (HN2), became available for the treatment of human malignant disease. It was soon apparent that this agent was able to produce objective responses in patients with lymphomatous disease. After this advance in cancer chemotherapy, a variety of alkylating agents and other chemicals have become available for the treatment of malignant lymphomas.
In addition to the alkylating agents a new group of plant alkaloids are now available for the treatment of these diseases. Adrenal steroids may be helpful in the primary therapy of these diseases as well as helping to alleviate the hemologic disorders
Gold GL, Shnider BI, Lynch JJ. Current Therapy of Malignant Lymphomas.. Ann Intern Med. ;62:1092–1093. doi: 10.7326/0003-4819-62-5-1092_3
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Published: Ann Intern Med. 1965;62(5):1092-1093.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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