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Four leading authorities in the field present in five chapters a composite and comprehensive coverage of our enlarged understanding of Tay-Sachs' disease.
Leading on from an historical account of the disease, the clinical features are described. It is stressed that affected infants do not in fact appear normal during the first 4 to 6 months of life but that the characteristic motor response to sound can be elicited within a few weeks of birth. Pathogenesis and evolution are traced through gross and histologic anatomy and more clearly delineated with the refinements of histochemistry and electron microscopy. Of special interest is
Tay-Sachs' Disease.. Ann Intern Med. 1965;62:1104. doi: 10.7326/0003-4819-62-5-1104_1
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Published: Ann Intern Med. 1965;62(5):1104.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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