ARMIN E. GOOD, M.D.; ROBERT P. CHRISTOPHER, M.D.; GEORGE H. KOEPKE, M.D.; LEONARD F. BENDER, M.D.; MICHAEL E. TARTER, PH.D.
As far back as the mid-nineteenth century, authors dealing with rheumatoid arthritis have commented upon associated symptoms suggesting neurologic disease (1). Features suggestive of peripheral neuropathy, in particular, have included paresthesias, radiating pains, vasomotor dysfunction, edema, and weakness. Histopathological changes in the peripheral nervous system have been described (2, 3). Objective signs, however, of peripheral neuropathy have been rare indeed in any unselected series of patients with rheumatoid arthritis (4, 5). Thus, in neurological circles, rheumatoid neuropathy has not received recognition as an entity (6). Since the introduction of corticosteroids, there has been considerable interest in cases of rheumatoid arthritis
GOOD AE, CHRISTOPHER RP, KOEPKE GH, et al. Peripheral Neuropathy Associated with Rheumatoid Arthritis: A Clinical and Electrodiagnostic Study of 70 Consecutive Rheumatoid Arthritis Patients. Ann Intern Med. 1965;63:87–99. doi: https://doi.org/10.7326/0003-4819-63-1-87
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Published: Ann Intern Med. 1965;63(1):87-99.
Neurology, Neuropathy, Rheumatoid Arthritis, Rheumatology.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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