SATORU NAKAMOTO, M.D.; GEORGE DUNEA, M.B., M.R.C.P.; WILLEM J. KOLFF, M.D., F.A.C.P.; LAWRENCE J. MCCORMACK, M.D.
The prognosis of acute glomerulonephritis with severe or prolonged oliguria is grave (1-7). Repeated hemodialyses are justified for at least 6 weeks, to allow time for diuresis to occur (7). Needle biopsy is helpful in assessing prognosis (8, 9) and possibly in avoiding what would be fruitless efforts in treatment. Although there is no evidence that adrenocorticotropic hormone (ACTH) or steroids favorably influence the long-term prognosis of glomerulonephritis (10, 11), there is a basis for administering high doses of corticosteroids to patients having severe oliguria in the hope that diuresis will ensue.
The present report concerns a series of nine
NAKAMOTO S, DUNEA G, KOLFF WJ, MCCORMACK LJ. Treatment of Oliguric Glomerulonephritis with Dialysis and Steroids. Ann Intern Med. 1965;63:359–368. doi: 10.7326/0003-4819-63-3-359
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Published: Ann Intern Med. 1965;63(3):359-368.
Nephrology, Renal Replacement Therapy.
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