MILTON G. CRANE, M.D., F.A.C.P.; JOHN J. HARRIS, M.D., F.A.C.P.; RAYMOND HERBER, M.D.
Primary aldosteronism is a syndrome characterized by hypokalemic alkalosis and hypertension. Benign adrenal cortical adenomas have been the cause of this syndrome in most of the patients reported in the literature. A few patients have had a malignancy as the cause of their defect. This is a case report of a patient with typical clinical and laboratory findings of primary aldosteronism caused by an adrenocortical carcinoma.
The patient was a 64-year-old female (Figure 1) who was first seen at the White Memorial Clinic in April, 1963, for hypertension and weakness. The patient was first aware that she had
CRANE MG, HARRIS JJ, HERBER R. Primary Aldosteronism Due to an Adrenal Carcinoma. Ann Intern Med. ;63:494–503. doi: 10.7326/0003-4819-63-3-494
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Published: Ann Intern Med. 1965;63(3):494-503.
Adrenal Disorders, Endocrine and Metabolism, Endocrine Cancer, Hematology/Oncology.
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