ALBERT SJOERDSMA, M.D., PH.D.; SIDNEY UDENFRIEND, PH.D.; HARRY KEISER, M.D.; E. CARWILE LEROY, M.D.
Dr. Albert Sjoerdsma: Collagen is one of the scleroproteins and accounts for about 30% of the body proteins. It exerts an architectural function throughout the body, most notably in skin, tendons, cartilage, blood vessels, connective tissue, organ capsules, and bone matrix. It confers the ultimate in "togetherness" and, except in psychiatry, is responsible for making one an "intact" individual. It is of fundamental importance in the pathogenesis of various diseases, in the processes of growth and aging, and of course in the healing of wounds. Use of the term "collagen disease" in clinical medicine has served at least as a
SJOERDSMA A, UDENFRIEND S, KEISER H, et al. Hydroxyproline and Collagen Metabolism: Clinical Implications: Combined Clinical Staff Conference at the National Institutes of Health. Ann Intern Med. 1965;63:672–694. doi: https://doi.org/10.7326/0003-4819-63-4-672
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Published: Ann Intern Med. 1965;63(4):672-694.
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