Gilbert Callis, M.D.; Charles Tam, M.D.; Chi Kong Liu, M.D., F.A.C.P.
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Digitalization has been used prophylactically in surgical patients with cardiovascular disease. However, we have encountered several incidences of fatal digitalis toxicity in patients receiving acute digitalization. This study reviews consecutively 198 patients with cardiovascular disease and 298 patients without cardiovascular disease, over age of 40, undergoing major surgery in a 12-month period. Seventy-seven of the 198 patients with cardiovascular disease required long-term digitalization. Twelve of the 77 patients died, with a mortality rate of 15.6%. These deaths were not related to digitalis toxicity. In contrast, 22 of 39 digitalized patients with and without cardiovascular disease died (mortality rate, 56%). Eleven
Callis G, Tam C, Liu CK. Digitalis Therapy in Surgical Patients With or Without Cardiovascular Disease.. Ann Intern Med. 1965;63:903–904. doi: https://doi.org/10.7326/0003-4819-63-5-903_3
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Published: Ann Intern Med. 1965;63(5):903-904.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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