Gerald J. Kavanaugh, M.D. (Associate); Alexander Schirger, M.D., F.A.C.P.; John A. Spittell Jr., M.D., F.A.C.P.
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To determine the influence of improved diagnostic methods on the etiologic classification of malignant hypertension (Group 4, Keith-Wagener-Barker), we reviewed the cases of 100 consecutive patients with malignant hypertension seen at the Mayo Clinic between 1958 and 1962; 81% were men, and the ages ranged from 5 to 75 years, averaging 46.8 years.
In 65% of the cases, essential hypertension was classified. The types of secondary hypertension diagnosed were renal parenchymal disease (19%), renal artery disease (7%), periarteritis nodosa (3%), scleroderma (2%), Kimmelstiel-Wilson disease (2%), Cushing's disease (1%), and intermediate (1%).
There was a progressive, although modest, decrease in the
Kavanaugh GJ, Schirger A, Spittell JA. The Etiologic Spectrum of Malignant Hypertension.. Ann Intern Med. ;63:904. doi: 10.7326/0003-4819-63-5-904_1
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Published: Ann Intern Med. 1965;63(5):904.
Cardiology, Coronary Risk Factors, Hypertension, Nephrology.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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