Joel T. Hamburger, M.D. (Associate); J. Martin Miller, M.D., F.A.C.P.; George Kadian, M.D.; Herbert W. Rossin, M.D.
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A low radioiodine uptake, with a symmetrical, patchy and irregular distribution of the tracer on scintigram, and a high normal or modestly elevated protein-bound iodine (PBI), have been considered characteristic of subacute thyroiditis. However, this static concept is inadequate to describe the dynamic changes that may be observed in patients with this disorder. The uptake and scintigram pattern observed depend upon the following: (1) The precise point in the evolution of the disease at which the tracer studies are performed; (2) the extent to which the disease involves the parenchyma of the gland; (3) the severity and persistence of the
Hamburger JT, Miller JM, Kadian G, Rossin HW. Subacute Thyroiditis: Evolution Depicted by Serial I131 Scintigram.. Ann Intern Med. ;63:909. doi: 10.7326/0003-4819-63-5-909_1
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Published: Ann Intern Med. 1965;63(5):909.
Endocrine and Metabolism, Thyroid Disorders.
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