Donald O. Castell
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Divers investigators have proposed that the oral ammonia tolerance test can be utilized to evaluate the presence of portal-systemic collateral circulation in patients with hepatic cirrhosis. In addition, it has been shown that there is a high degree of association between collateral circulation and portal hypertension. This study was under-taken to evaluate the correlation between the abnormal oral ammonia tolerance test and portal hypotension in patients with cirrhosis of the liver.
The arterial ammonia tolerance test was studied in 18 patients with hepatic cirrhosis, and the results were compared with the portal pressure as measured by hepatic vein wedge pressure.
Castell DO. The Ammonia Tolerance Test: An Index of Portal Hypertension.. Ann Intern Med. 1965;63:909. doi: https://doi.org/10.7326/0003-4819-63-5-909_2
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Published: Ann Intern Med. 1965;63(5):909.
Gastroenterology/Hepatology, Liver Disease.
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