R. K. Nixon, M.D.
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In a recent study we have determined a frequent A association of marrow mastocytosis with lymphocytic dyscrasias. Although increases in mast cells have been encountered occasionally with lymphocytoses in other diseases (miliary tuberculosis, locally invasive carcinoma), only in urticaria pigmentosa has a corresponding degree of mastocytosis been observed. Moderate marrow mast cell increases are found in the areas of normal lymph follicles.
A more impressive demonstration of this association of mast cell and lymphocytic disease has been displayed in two of our patients. The first presented with episodic flushing, urticaria pigmentosa, adenopathy, and hepatosplenomegaly. Laboratory data included marrow mastocytosis and
Nixon RK. The Relation of Mastocytosis and Lymphomatous Disease.. Ann Intern Med. 1965;63:912–913. doi: https://doi.org/10.7326/0003-4819-63-5-912_3
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Published: Ann Intern Med. 1965;63(5):912-913.
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