ROBERT M. DONATI, M.D.; MARY ANNE WARNECKE, B.S.; NEIL I. GALLAGHER, M.D.
Alteration of thyroid function influences the synthesis and life span of the red blood cell. Anemia occurs in hypothyroid patients (1, 2) and in animals after thyroid ablation when there has been a concurrent decrease in metabolic rate (3, 4). Reversal of this decreased erythropoiesis by various metabolic stimulants (5) supports the concept that the anemia is a physiological adaptation to the decrease in total tissue oxygen requirement. Conversely, thyroid hormones augment erythropoiesis in euthyroid rodents and dogs (6-8). In addition, significant increases in the red blood cell mass of thyrotoxic patients have been noted by Muldowny, Crooks, and Wayne
DONATI RM, WARNECKE MA, GALLAGHER NI. Ferrokinetics in Hyperthyroidism. Ann Intern Med. 1965;63:945–950. doi: https://doi.org/10.7326/0003-4819-63-6-945
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Published: Ann Intern Med. 1965;63(6):945-950.
Endocrine and Metabolism, Thyroid Disorders.
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