DUANE W. TAEBEL, M.D.; JOAO C. PROLLA, M.D.; JOSEPH B. KIRSNER, M.D., F.A.C.P.
Concern for the early diagnosis of cancer has been one of the main factors in the development of diagnostic methods for the examination of the upper gastrointestinal tract: X ray, endoscopy, and more recently, exfoliative cytology. The latter technique was advocated initially over 100 years ago by Beale (1) who, in 1858, examined vomitus by paraffin block technique. In 1909, Marini (2) conceived the idea that fresh material obtained by gastric lavage might contain better preserved malignant cells. He was able to obtain malignant cells in 32 of 37 gastric and esophageal carcinomas, a remarkable accomplishment considering that the preparations
TAEBEL DW, PROLLA JC, KIRSNER JB. Exfoliative Cytology in the Diagnosis of Stomach Cancer. Ann Intern Med. ;63:1018–1026. doi: 10.7326/0003-4819-63-6-1018
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Published: Ann Intern Med. 1965;63(6):1018-1026.
Gastric Cancer, Gastroenterology/Hepatology, Gastrointestinal Cancer, Hematology/Oncology.
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