R. GORDON DOUGLAS JR., M.D.; ROBERT H. ALFORD, M.D.; THOMAS R. CATE, M.D.; ROBERT B. COUCH, M.D.
Recent studies have shown that most acute upper respiratory illnesses in humans are associated with infections caused by a variety of viruses. In spite of the diversity of etiologic agents, the illnesses produced by these viruses are remarkably similar. There is little reliable information concerning the leukocyte response in many of these naturally occurring illnesses because of their mildness and short duration. In addition, since contradictory leukocyte changes have been reported in influenza and adenovirus illness (1-4), it appeared that further observations of the patterns of leukocyte response in these and other viral respiratory infections might yield information of significance.
DOUGLAS RG, ALFORD RH, CATE TR, et al. The Leukocyte Response During Viral Respiratory Illness in Man. Ann Intern Med. 1966;64:521–530. doi: 10.7326/0003-4819-64-3-521
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Published: Ann Intern Med. 1966;64(3):521-530.
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