Robert D. Leeper, M.D.; Ralph Marcove, M.D.; Morton K. Schwartz, Ph.D.; Rulon W. Rawson, M.D., F.A.C.P.
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An increased incidence of thyroid abnormalities, elevations of serum beta globulin proteins and type A blood group was found in a prospective study of 42 patients with Paget's disease. Thirty-three per cent of the patients had goiters or a previous history of thyroid abnormalities. Seven patients had undergone thyroidectomy. Two patients had Hashimoto's thyroiditis, and 4 patients had presumptive evidence of this disease. Four patients were hypothyroid at the time of examination.
Fifteen of 28 patients (54%) had elevated serum beta globulins. This increase was highly significant (P = < 0.01) when compared to the incidence (10%) of increased beta
Leeper RD, Marcove R, Schwartz MK, et al. The Increase of Thyroid Abnormalities, Elevated Serum Beta Globulins and Type A Blood Group in Paget's Disease.. Ann Intern Med. 1966;64:1171. doi: 10.7326/0003-4819-64-5-1171_2
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Published: Ann Intern Med. 1966;64(5):1171.
Endocrine and Metabolism, Thyroid Disorders.
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Print ISSN: 0003-4819 | Online ISSN: 1539-3704
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