Richard D. Carr, M.D.; Eldred B. Heisel, M.D.
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The CRST syndrome is a recently defined symptom-complex consisting of (1) calcinosis cutis, (2) Raynaud's phenomenon, (3) sclerodactyly and (4) telangiectasis closely resembling hereditary hemorrhagic telangiectasis. Seven cases observed by the authors during the past year are presented in tabular form in regard to clinical findings, laboratory abnormalities, and histopathology. Specimen photographs and roentgenographic slides illustrating the characteristic findings are shown.
Comparison of the CRST syndrome with the common acrosclerotic type of scleroderma is made, revealing several common features and a basic similarity between the two. The CRST syndrome does appear to pursue a prolonged and more benign course. However,
Carr RD, Heisel EB. CRST Syndrome.. Ann Intern Med. 1966;64:1174. doi: https://doi.org/10.7326/0003-4819-64-5-1174_2
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Published: Ann Intern Med. 1966;64(5):1174.
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