Robert W. Talley, M.D., F.A.C.P.; Robert M. O. Brayan, M.D.; Emily L. San Diego, M.D.; Michael J. Brennan, M.D., F.A.C.P.; John Burrows, M.D.
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Carcinoma of the ovary accounts for approximately 5% of all female cancers, and because it is frequently not diagnosed until late, management of the disease is frequently palliative. Because of the complications encountered in recurrent disease such as pulmonary symptoms due to pleural effusion, electrolyte imbalance associated with prolonged partial obstruction, internists frequently are called to help with the management of these patients. In a review of 100 patients with recurrent ovarian malignancies, three patients with hypercalcemia without bone metastases were encountered, two patients with pericardial effusion required repeated pericardiocenteses as well as many patients with severe electrolyte disturbances.
Talley RW, Brayan RMO, San Diego EL, et al. Recurrent Carcinoma of the Ovary, Unusual Manifestations and Management Problems.. Ann Intern Med. 1966;64:1177. doi: https://doi.org/10.7326/0003-4819-64-5-1177_1
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Published: Ann Intern Med. 1966;64(5):1177.
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