Kurt Lange, M.D., F.A.C.P.; Gerhard Treser, M.D.; Edward Wasserman, M.D.; Theodore Ehrenreich, M.D.; Richard Ores, M.D.; Antonia Ty, M.D.
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Twenty-one patients (20 children and 1 adult) with acute poststreptococcal glomerulonephritis were biopsied within a month of onset of their disease and again 10 to 84 months later. The biopsies were studied by light- and electron microscopy and by immunohistology for gamma globulin and complement. At the time of repeat biopsy all patients were clinically well, and 15 had no abnormal laboratory findings. Of six remaining patients (28%), one had a 1+ proteinuria, five a trace proteinuria, two of them with more than 1.5 million RBC/mm3 in the Addis counts.
Among the patients rebiopsied 20 months or more after the
Lange K, Treser G, Wasserman E, Ehrenreich T, Ores R, Ty A. Clinical, Morphologic and Immunologic Studies on the Natural History of Acute Post-Streptococcal Glomerulonephritis.. Ann Intern Med. ;64:1180–1181. doi: 10.7326/0003-4819-64-5-1180_4
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Published: Ann Intern Med. 1966;64(5):1180-1181.
Autoimmune Kidney Disease, Nephrology, Rheumatology.
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