John R. Graham, M.D., F.A.C.P.; Howard I. Suby, M.D.
This content is PDF only. Please click on the PDF icon to access.
Twente-seven patients who have developed retroperitoneal fibrosis while taking methysergide (Sansert®) for headache have been collected. In 14 patients the diagnosis was proved at operation. In 13 it was clinically established, and the process regressed upon withdrawal of the drug. Fibrosis involving the root of the aorta, heart valves, and pulmonary tissue during methysergide therapy will also be discussed and theories presented regarding the possible relationship of the drug to these conditions and the possible mechanisms involved.
Graham JR, Suby HI. Fibrotic Conditions Occurring During Methysergide Therapy for Headache.. Ann Intern Med. 1966;64:1184. doi: 10.7326/0003-4819-64-5-1184_2
Download citation file:
Published: Ann Intern Med. 1966;64(5):1184.
Copyright © 2019 American College of Physicians. All Rights Reserved.
Print ISSN: 0003-4819 | Online ISSN: 1539-3704
Conditions of Use