VISITH SITPRIJA, M.D., PH.D.; CHARN POCHANUGOOL, M.D.; CHANYO BENYAJATI, M.D.; CHARAS SUWANWELA, M.D.
It was observed by Claude Bernard that resection of the splanchnic nerves results in an increased urine flow (1). Although a number of laboratory and clinical investigations have been carried out to study the effect of denervation of the kidney on renal function (2-7), the mechanism responsible for diuresis remains unsettled. Some investigators have suggested that renal denervation depresses tubular transport of sodium (2-4); others, from the evidence that there is a rise in glomerular filtration rate and renal flow after denervation, have concluded that natriuresis is the result of changes in renal hemodynamics (5-7).
While attention has been focused
SITPRIJA V, POCHANUGOOL C, BENYAJATI C, et al. Polydipsia and Polyuria Associated with Quadriplegia. Ann Intern Med. 1966;65:62–68. doi: 10.7326/0003-4819-65-1-62
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Published: Ann Intern Med. 1966;65(1):62-68.
Nephrology, Neurology, Urological Disorders.
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