HARRY RUBIN, M.D.
Chronic neutrophilic leukemia is uncommon, and there is some question as to whether it should be considered a distinct disease entity. Few case reports exist in the literature. In one of the early descriptions of two cases (1), the authors concluded that this disorder was a variant of chronic myelogenous leukemia. The recent introduction of chromosomal analysis has been helpful in distinguishing chronic myelogenous leukemia within the group of myeloproliferative disorders, as have cytochemical techniques.
We recently had the opportunity of studying a patient whose case closely resembled the previously described cases of chronic neutrophilic leukemia clinically and hematologically. By
RUBIN H. Chronic Neutrophilic Leukemia. Ann Intern Med. ;65:93–100. doi: 10.7326/0003-4819-65-1-93
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Published: Ann Intern Med. 1966;65(1):93-100.
Hematology/Oncology, Hospital Medicine, Rheumatology.
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