ROY HERTZ, PH.D., M.D.; WILLIAM D. ODELL, M.D., PH.D.; GRIFF T. ROSS, M.D., PH.D.
Dr. Roy Hertz: Patients with amenorrhea represent a significant portion of the diagnostic problems seen by the physician interested in reproductive endocrinology. Such diagnostic problems can be subdivided into two major categories: one, those patients who have never had menses (so-called primary amenorrhea), and two, those who have had normal menses in the past but who present with amenorrhea (so-called secondary amenorrhea). The patient presenting with primary amenorrhea is the subject of this discussion. Physiologic considerations and clinical studies derived from these will be presented initially. Finally, the application of these principles to a series of illustrative patients seen on
HERTZ R, ODELL WD, ROSS GT. Diagnostic Implications of Primary Amenorrhea: Combined Clinical Staff Conference at the National Institutes of Health. Ann Intern Med. 1966;65:800–820. doi: 10.7326/0003-4819-65-4-800
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Published: Ann Intern Med. 1966;65(4):800-820.
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